PGLYRP1 anticorps (AA 65-150)

N° du produit ABIN872537

Détail du produit anti-PGLYRP1 anticorps

Antigène: PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))

Épitope: AA 65-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGLYRP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PGRPS

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PGLYRP1

Antigène: PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))

Autre désignation: PGRPS (PGLYRP1 Produits)

Synonymes: anticorps PGLYRP1, anticorps PGLYRP, anticorps pgrp, anticorps tag7, anticorps pgrps, anticorps pglyrp, anticorps pgrp-s, anticorps tnfsf3l, anticorps MGC108330, anticorps MGC108469, anticorps PGRP-SC1a, anticorps si:dkey-113g17.4, anticorps si:ch211-202c21.3, anticorps PGRP, anticorps PGRP-S, anticorps PGRPS, anticorps TAG7, anticorps TNFSF3L, anticorps Pglyrp, anticorps Tag7, anticorps Tasg7, anticorps Tnfsf3l, anticorps Pgrp, anticorps peptidoglycan recognition protein 1, anticorps peptidoglycan recognition protein 1 L homeolog, anticorps peptidoglycan recognition protein 5, anticorps PGLYRP1, anticorps pglyrp1.L, anticorps pglyrp1, anticorps pglyrp5, anticorps Pglyrp1

Sujet:

Synonyms: Peptidoglycan recognition protein 1, Peptidoglycan recognition protein, PGLYRP, PGLYRP1, PGRP, PGRP S, PGRP-PEN, PGRP-S, TAG7, TNFSF 3L, TNFSF3L, PGRP1_HUMAN.

Background: The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRPS, PGRPIA, and PGRP-I-beta) define a new family of human pattern recognition molecules. PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood. PGRPS is present in neutrophils and inhibits growth of Gram-positive bacteria and, therefore, may function as a neutrophil antibacterial protein. However, PGRPS may have another, as yet unidentified function because in humans it is expressed in the bone marrow 50100 times higher than in neutrophils.

ID gène: 8993

Pathways: Activation of Innate immune Response