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IL-6 anticorps (AA 51-150)

IL6 Reactivité: Humain, Souris, Porc, Lapin, Boeuf (Vache) WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN872547
  • Antigène Voir toutes IL-6 (IL6) Anticorps
    IL-6 (IL6) (Interleukin 6 (IL6))
    Épitope
    • 19
    • 18
    • 17
    • 15
    • 15
    • 14
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivité
    • 193
    • 129
    • 75
    • 24
    • 20
    • 20
    • 14
    • 12
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    Humain, Souris, Porc, Lapin, Boeuf (Vache)
    Hôte
    • 196
    • 88
    • 68
    • 16
    • 4
    • 3
    • 2
    Lapin
    Clonalité
    • 219
    • 155
    • 1
    Polyclonal
    Conjugué
    • 199
    • 59
    • 28
    • 12
    • 12
    • 9
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL-6 est non-conjugé
    Application
    • 269
    • 138
    • 104
    • 59
    • 52
    • 51
    • 40
    • 40
    • 37
    • 31
    • 25
    • 25
    • 19
    • 19
    • 14
    • 10
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Boeuf (Vache), Humain, Souris, Porc, Lapin
    Homologie
    Cow,Sheep,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human IL-6
    Isotype
    IgG
    Top Product
    Discover our top product IL6 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Chen, Wu, Jiang, Zhou, Wang, Yao, Yi, Gou, Yang: "Isoliquiritigenin inhibits the growth of multiple myeloma via blocking IL-6 signaling." dans: Journal of molecular medicine (Berlin, Germany), Vol. 90, Issue 11, pp. 1311-9, (2012) (PubMed).

  • Antigène
    IL-6 (IL6) (Interleukin 6 (IL6))
    Autre désignation
    IL-6 (IL6 Produits)
    Synonymes
    anticorps BSF2, anticorps HGF, anticorps HSF, anticorps IFNB2, anticorps IL-6, anticorps Il-6, anticorps ILg6, anticorps Ifnb2, anticorps il6, anticorps CHIL-6, anticorps interleukin 6, anticorps interleukin-6, anticorps IL6, anticorps Il6, anticorps il-6, anticorps IL-6
    Sujet

    Synonyms: HGF, HSF, BSF2, IL-6, IFNB2, Interleukin-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IL6

    Background: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.

    ID gène
    3569
    UniProt
    P05231
    Pathways
    Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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