AICDA anticorps (AA 101-198)

N° du produit ABIN872554

Détail du produit anti-AICDA anticorps

Antigène: AICDA (Activation-Induced Cytidine Deaminase (AICDA))

Épitope: AA 101-198

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AICDA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human AICDA

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-AICDA (ABIN872554)

Demberg, Mohanram, Musich, Brocca-Cofano, McKinnon, Venzon, Robert-Guroff: "Loss of marginal zone B-cells in SHIVSF162P4 challenged rhesus macaques despite control of viremia to low or undetectable levels in chronic infection." dans: Virology, Vol. 484, pp. 323-333, (2015) (PubMed).

Détails sur AICDA

Antigène: AICDA (Activation-Induced Cytidine Deaminase (AICDA))

Autre désignation: AICDA (AICDA Produits)

Synonymes: anticorps AID, anticorps ARP2, anticorps CDA2, anticorps HIGM2, anticorps Aid, anticorps Arp2, anticorps aid, anticorps AICDA, anticorps arp2, anticorps cda2, anticorps higm2, anticorps xlaid, anticorps activation induced cytidine deaminase, anticorps activation-induced cytidine deaminase, anticorps activation-induced cytidine deaminase L homeolog, anticorps AICDA, anticorps Aicda, anticorps aicda, anticorps aicda.L

Sujet:

Synonyms: AID, ARP2, CDA2, HIGM2, HEL-S-284, Single-stranded DNA cytosine deaminase, Activation-induced cytidine deaminase, Cytidine aminohydrolase, AICDA

Background: Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.

ID gène: 57379

UniProt: Q9GZX7

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Production of Molecular Mediator of Immune Response