FAM3C anticorps (AA 151-227)

N° du produit ABIN872576

Détail du produit anti-FAM3C anticorps

Antigène: FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))

Épitope: AA 151-227

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM3C est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FAM3C

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FAM3C

Antigène: FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))

Autre désignation: FAM3C (FAM3C Produits)

Synonymes: anticorps ILEI, anticorps D6Wsu176e, anticorps Ilei, anticorps wu:fb99h11, anticorps wu:fi35h03, anticorps zgc:55444, anticorps zgc:77090, anticorps family with sequence similarity 3 member C, anticorps family with sequence similarity 3, member C, anticorps family with sequence similarity 3 member C L homeolog, anticorps fam3c, anticorps FAM3C, anticorps Fam3c, anticorps fam3c.L

Sujet:

Synonyms: Fam3c, FAM3C_HUMAN, family with sequence similarity 3, member C, GS3786,ILEI, Interleukin-like EMT inducer, Predicted osteoblast protein, Protein FAM3C.

Background: ILEI is a 227 amino acid, ubiquitously expressed protein containing an amino-terminal signal peptide. Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis. Also, overexpression of ILEI results in loss of ZO-1, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, which has been shown to influence loss of polarity and invasiveness. Due to this evidence, it is suspected that ILEI cooperates with oncogenic Ras to cause TGF-independent Emt and its overexpression is correlated with the invasion, metastasis and survival in a variety of cancers.

ID gène: 10447