DNASE2 anticorps (AA 25-90)

N° du produit ABIN872658

Détail du produit anti-DNASE2 anticorps

Antigène: DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))

Épitope: AA 25-90

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNASE2 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DNase II alpha

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-DNASE2 (ABIN872658)

Takahashi, Loo, Okada, Kamachi, Watanabe, Wakita, Watanabe, Kawamoto, Miyata, Barber, Ohtani, Hara: "Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells." dans: Nature communications, Vol. 9, Issue 1, pp. 1249, (2018) (PubMed).

Détails sur DNASE2

Antigène: DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))

Autre désignation: DNase 2 alpha (DNASE2 Produits)

Synonymes: anticorps CG7780, anticorps DNase, anticorps DNase 1, anticorps DNase-1, anticorps DNase1, anticorps Dmel\\CG7780, anticorps dDNase II, anticorps dnase2, anticorps MGC80103, anticorps DNASE2, anticorps LOC733868, anticorps fa92d01, anticorps wu:fa56d08, anticorps wu:fa92d01, anticorps DDBDRAFT_0188966, anticorps DDBDRAFT_0252883, anticorps DDB_0188966, anticorps DDB_0252883, anticorps Dnase2, anticorps DNASE2A, anticorps DNL, anticorps DNL2, anticorps Dnase2a, anticorps Deoxyribonuclease II, anticorps deoxyribonuclease II, lysosomal L homeolog, anticorps deoxyribonuclease 2, lysosomal, anticorps deoxyribonuclease II, lysosomal, anticorps deoxyribonuclease II, anticorps deoxyribonuclease II alpha, anticorps DNaseII, anticorps dnase2.L, anticorps DNASE2, anticorps dnase2, anticorps Dnase2a, anticorps Dnase2

Sujet:

Synonyms: DNL, DNL2, DNASE2A, Deoxyribonuclease-2-alpha, Acid DNase, Deoxyribonuclease II alpha, DNase II alpha, Lysosomal DNase II, R31240_2, DNASE2

Background: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

ID gène: 1777

UniProt: O00115