ARRDC3 anticorps (AA 178-215)

N° du produit ABIN872868

Détail du produit anti-ARRDC3 anticorps

Antigène: ARRDC3 (Arrestin Domain Containing 3 (ARRDC3))

Épitope: AA 178-215

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARRDC3 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ARRDC3 corresponding to amino acids 178-215.

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ARRDC3

Antigène: ARRDC3 (Arrestin Domain Containing 3 (ARRDC3))

Autre désignation: ARRDC3 (ARRDC3 Produits)

Synonymes: anticorps TLIMP, anticorps AI450344, anticorps mKIAA1376, anticorps LRRGT00048, anticorps ARRDC3, anticorps arrdc3, anticorps si:dkey-172m14.3, anticorps wu:fc21e01, anticorps zgc:136956, anticorps MGC131006, anticorps DKFZp469D0714, anticorps zgc:92034, anticorps arrestin domain containing 3, anticorps arrestin domain containing 3a, anticorps arrestin domain containing 3 S homeolog, anticorps arrestin domain containing 3b, anticorps ARRDC3, anticorps Arrdc3, anticorps arrdc3, anticorps arrdc3a, anticorps arrdc3.S, anticorps arrdc3b

Sujet:

Synonyms: ARRDC 3, Arrestin domain containing protein 3, KIAA1376, Thioredoxin binding protein 2 like inducible membrane, TLIMP, ARRD3_HUMAN.

Background: The arrestins are a family of proteins that are important for regulating signal transduction within cells. Arrestins are part of a conserved two step mechanism for regulating the activity of G-protein coupled receptors (GPCRs). In response to a stimulus, GPCRs activate a heterotrimeric G protein. In order to turn off this response, or adapt to a constant stimulus, activated receptors need to be silenced. The first step is phosphorylation by a class of serine/threonine kinases called G protein coupled receptor kinases (GRKs). This phosphorylation specifically marks the activated receptor for arrestin binding. Once arrestin is bound to the receptor it is unable to signal further. Recent research continues to expand the known actions of arrestins, which can bind to other classes of receptors and can directly activate signaling pathways on their own. Different arrestins (visual arrestin (or Arrestin 1), beta-arrestin 1 (or Arrestin 2) and beta-arrestin 2 (or Arrestin 3) can reduce the activity of their target GPCRs in several different ways.

ID gène: 57561