RBPJ anticorps (AA 101-200)
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- Antigène Voir toutes RBPJ Anticorps
- RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
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Épitope
- AA 101-200
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RBPJ est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Dog,Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human RBPJK
- Isotype
- IgG
- Top Product
- Discover our top product RBPJ Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
- Autre désignation
- RBPJK (RBPJ Produits)
- Synonymes
- anticorps AOS3, anticorps CBF1, anticorps IGKJRB, anticorps IGKJRB1, anticorps KBF2, anticorps RBP-J, anticorps RBPJK, anticorps RBPSUH, anticorps SUH, anticorps csl, anticorps AI843960, anticorps Igkjrb, anticorps Igkrsbp, anticorps RBP-J kappa, anticorps RBPjk, anticorps Rbpsuh, anticorps Su(H), anticorps XSu(H), anticorps xsu(h)1, anticorps Su(H)1, anticorps Su(h)A, anticorps ik:tdsubc_1e8, anticorps rbpj, anticorps rbpsuh, anticorps xx:tdsubc_1e8, anticorps Su(H)2, anticorps su(h)B, anticorps recombination signal binding protein for immunoglobulin kappa J region, anticorps recombination signal binding protein for immunoglobulin kappa J region S homeolog, anticorps recombination signal binding protein for immunoglobulin kappa J region a, anticorps recombination signal binding protein for immunoglobulin kappa J region b, anticorps RBPJ, anticorps Rbpj, anticorps rbpj.S, anticorps rbpja, anticorps rbpjb
- Sujet
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Synonyms: SUH, csl, AOS3, CBF1, KBF2, RBP-J, RBPJK, IGKJRB, RBPSUH, IGKJRB1, Recombining binding protein suppressor of hairless, CBF-1, J kappa-recombination signal-binding protein, RBP-J kappa, RBP-JK, Renal carcinoma antigen NY-REN-30, RBPJ
Background: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA.
- ID gène
- 3516
- UniProt
- Q06330
- Pathways
- Signalisation Notch, Stem Cell Maintenance, Smooth Muscle Cell Migration
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