Importin 9 anticorps (AA 601-729)

N° du produit ABIN873167

Détail du produit anti-Importin 9 anticorps

Antigène: Importin 9 (IPO9)

Épitope: AA 601-729

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Importin 9 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Importin 9

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Importin 9

Antigène: Importin 9 (IPO9)

Autre désignation: Importin 9 (IPO9 Produits)

Synonymes: anticorps Imp9, anticorps 0710008K06Rik, anticorps AI845704, anticorps C78347, anticorps Ranbp9, anticorps mKIAA1192, anticorps zgc:66429, anticorps wu:fc23d12, anticorps MGC81741, anticorps IPO9, anticorps DDBDRAFT_0205722, anticorps DDBDRAFT_0229883, anticorps DDB_0205722, anticorps DDB_0229883, anticorps RGD1561940, anticorps RanBPM, anticorps RanBP9, anticorps bpm-l, anticorps bpm90, anticorps ranbp9, anticorps ranbp9-a, anticorps ranbp9-b, anticorps ranbp9b, anticorps cb457, anticorps zgc:158650, anticorps importin 9, anticorps importin 9 L homeolog, anticorps RAN binding protein 9, anticorps RAN binding protein 9 L homeolog, anticorps IPO9, anticorps Ipo9, anticorps ipo9, anticorps ipo9.L, anticorps cnrP, anticorps Ranbp9, anticorps ranbp9.L, anticorps RANBP9, anticorps ranbp9

Sujet:

Synonyms: B cell antigen receptor Ig beta associated protein 1, BPM 90, BPM L, BPM-L, BPM90, BPML, IBAP 1, Imp 9, Importin 9, Importin9, Importin-9, Novel centrosomal protein RanBPM, RAN binding protein 9, Ran binding protein centrosomal, Ran binding protein M, Ran BP9, Ran-binding protein 9, Ran-binding protein M, RANB9_HUMAN, RanBP 7, RANBP 9, RanBP7, RanBP9, RanBPM.

Background: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Involved in activation of androgen and glucocorticoid receptor in the presence of their cognate hormones. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.Tissue specificity: Ubiquitously expressed, with highest levels in testes, placenta, heart, and muscle, and lowest levels in lung. Within the brain, expressed predominantly by neurons in the gray matter of cortex, the granular layer of cerebellum and the Purkinje cells.

ID gène: 10048

Pathways: Protein targeting to Nucleus