SCARB2 anticorps (AA 181-280)
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- Antigène Voir toutes SCARB2 Anticorps
- SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
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Épitope
- AA 181-280
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SCARB2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Dog,Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Scavenger Receptor BII
- Isotype
- IgG
- Top Product
- Discover our top product SCARB2 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
- Abstract
- SCARB2 Produits
- Synonymes
- anticorps cd36l2, anticorps fi13c07, anticorps chunp6914, anticorps wu:fi13c07, anticorps SCARB2, anticorps scarb2, anticorps AMRF, anticorps CD36L2, anticorps EPM4, anticorps HLGP85, anticorps LGP85, anticorps LIMP-2, anticorps LIMPII, anticorps SR-BII, anticorps 9330185J12Rik, anticorps Cd36l2, anticorps MLGP85, anticorps LimpII, anticorps scavenger receptor class B, member 2a, anticorps scavenger receptor class B member 2, anticorps scavenger receptor class B, member 2, anticorps scarb2a, anticorps SCARB2, anticorps scarb2, anticorps Scarb2
- Sujet
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Synonyms: AMRF, EPM4, LGP85, CD36L2, HLGP85, LIMP-2, LIMPII, SR-BII, Lysosome membrane protein 2, 85 kDa lysosomal membrane sialoglycoprotein, CD36 antigen-like 2, Lysosome membrane protein II, LIMP II, Scavenger receptor class B member 2, CD36, SCARB2, LIMP2
Background: High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain. Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI. SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues. Although the role of these scavenger receptors is not completely clear, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells. Therefore, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.
- ID gène
- 950
- UniProt
- Q14108
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