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TACC1 anticorps (AA 588-680)

TACC1 Reactivité: Souris, Rat ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN873222
  • Antigène Voir toutes TACC1 Anticorps
    TACC1 (Transforming, Acidic Coiled-Coil Containing Protein 1 (TACC1))
    Épitope
    • 10
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 588-680
    Reactivité
    • 31
    • 16
    • 1
    Souris, Rat
    Hôte
    • 30
    • 1
    Lapin
    Clonalité
    • 30
    • 1
    Polyclonal
    Conjugué
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TACC1 est non-conjugé
    Application
    • 24
    • 18
    • 6
    • 4
    • 2
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human TACC1
    Isotype
    IgG
    Top Product
    Discover our top product TACC1 Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    TACC1 (Transforming, Acidic Coiled-Coil Containing Protein 1 (TACC1))
    Autre désignation
    TACC1 (TACC1 Produits)
    Synonymes
    anticorps TACC1, anticorps DKFZp459A2134, anticorps Ga55, anticorps 4833447E04Rik, anticorps AA960202, anticorps B230378H13Rik, anticorps Tacc1a, anticorps transforming acidic coiled-coil containing protein 1, anticorps transforming, acidic coiled-coil containing protein 1, anticorps uncharacterized LOC100523215, anticorps TACC1, anticorps tacc1, anticorps Tacc1, anticorps LOC100523215
    Sujet

    Synonyms: Ga 55, Ga55, Gastric cancer antigen Ga 55, Gastric cancer antigen Ga55, KIAA1103, TACC 1, Taxin 1, Taxin1, transforming acidic coiled coil containing protein 1, DKFZp686K18126, TACC1_HUMAN.

    Background: TACC1 is one of three TACC family members, which are thought to be involved in breast tumorigenesis. TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15 % of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 8, 10, and 4. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner

    ID gène
    6867
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