CRTC2 anticorps (pSer171) (AbBy Fluor® 647)
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- Antigène Voir toutes CRTC2 Anticorps
- CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))
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Épitope
- pSer171
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CRTC2 est conjugé à/à la AbBy Fluor® 647
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Dog,Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from human CREB regulated transcription coactivator 2 around the phosphorylation site of Ser171
- Isotype
- IgG
- Top Product
- Discover our top product CRTC2 Anticorps primaire
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- Indications d'application
- FCM 1:20-100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))
- Autre désignation
- TORC2 (CRTC2 Produits)
- Synonymes
- anticorps CRTC2, anticorps TORC-2, anticorps TORC2, anticorps 4632407F12Rik, anticorps Torc2, anticorps mTORC2, anticorps RGD1308903, anticorps CREB regulated transcription coactivator 2, anticorps CRTC2, anticorps Crtc2
- Sujet
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Synonyms: TORC2, TORC-2, CREB-regulated transcription coactivator 2, Transducer of regulated cAMP response element-binding protein 2, Transducer of CREB protein 2, CRTC2
Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
- ID gène
- 200186
- UniProt
- Q53ET0
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis
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