ADAMTSL2 anticorps (AA 522-580) (AbBy Fluor® 647)
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- Antigène Voir toutes ADAMTSL2 Anticorps
- ADAMTSL2 (ADAMTS-Like 2 (ADAMTSL2))
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Épitope
- AA 522-580
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ADAMTSL2 est conjugé à/à la AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain
- Homologie
- Mouse,Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human ADAMTSL2
- Isotype
- IgG
- Top Product
- Discover our top product ADAMTSL2 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ADAMTSL2 (ADAMTS-Like 2 (ADAMTSL2))
- Autre désignation
- ADAMTSL2 (ADAMTSL2 Produits)
- Synonymes
- anticorps ADAMTSL2, anticorps GPHYSD1, anticorps A930008K15Rik, anticorps tcp-1, anticorps RGD1305459, anticorps ADAMTS-like 2, anticorps ADAMTS like 2, anticorps ADAMTS-like protein 2, anticorps ADAMTSL2, anticorps adamtsl2, anticorps LOC100589493, anticorps Adamtsl2
- Sujet
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Synonyms: ADAMTS like 2, ADAMTS like protein 2, ADAMTS-like protein 2, ADAMTSL 2, ADAMTSL-2, ADAMTSL2, ATL2_HUMAN.
Background: ADAMTS (A Disintegrin And Metalloproteinase Domain with Thrombospondin type 1 Modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer. ADAMTS protein family members contain an amino-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a carboxy-terminus that contains a varying number of Thrombospondin type 1 (TSP-1) motifs. ADAMTS-L2 (ADAMTS-like protein 2) is a 951 amino acid secreted protein that is highly expressed in lung, kidney and liver. Mutations in the gene encoding ADAMTS are the cause of geleophysic dysplasia, an autosomal recessive disorder characterized by cardiac vavular anomalies, short stature, thick skin and brachydactyly. In individuals affected with geleophysic dysplasia, there is a significant increase in total active TGF-beta 1 and nuclear locations of p-SAMD2 in fibroblasts. Interestingly, ADAMTS-L2 interacts with LTBP-1, a glycoprotein that is part of the platelet-derived TGF-beta 1 complex.
- ID gène
- 9719
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