APIP anticorps (AA 151-242) (AbBy Fluor® 555)
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- Antigène Voir toutes APIP Anticorps
- APIP (APAF1 Interacting Protein (APIP))
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Épitope
- AA 151-242
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp APIP est conjugé à/à la AbBy Fluor® 555
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human APIP
- Isotype
- IgG
- Top Product
- Discover our top product APIP Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- APIP (APAF1 Interacting Protein (APIP))
- Autre désignation
- Apaf1 Interacting Protein (APIP Produits)
- Synonymes
- anticorps APIP2, anticorps CGI29, anticorps MMRP19, anticorps dJ179L10.2, anticorps hAPIP, anticorps CGI-29, anticorps Mmrp19, anticorps RGD1564562, anticorps zgc:103619, anticorps APAF1 interacting protein, anticorps APAF1 interacting protein S homeolog, anticorps APIP, anticorps Apip, anticorps apip, anticorps apip.S
- Sujet
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Synonyms: MTNB_HUMAN, Apaf1 Interacting Protein, APIP2, CG129, CGI 29, MMRP19, MTRu 1 P dehydratase, Probable methylthioribulose 1 phosphate dehydratase.
Background: The mammalian homologues of the key cell death gene CED 4 in C. elegans has been identified recently from human and mouse and designated Apaf1 (for apoptosis protease activating factor 1). Apaf1 binds to cytochrome c (Apaf2) and caspase 9 (Apaf3), which leads to caspase 9 activation. Activated caspase 9 in turn cleaves and activates caspase 3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. A new Apaf1 Interacting Protein (APIP) also known as CG129 and MMRP19, has been identified as a negative regulator of ischemic injury. APIP competes with Caspase 9 binding site of Apaf1. APIP is predicted to code for a 204 amino acid. An isoform of APIP, APIP2 encodes a 242 amino acid protein, which is an alternative splicing variant differing in its N terminus from APIP. APIP transcript is ubiquitously expressed in most adult tissue with high expression in skeletal muscle, heart, and kidney.
- ID gène
- 51074
- Pathways
- Methionine Biosynthetic Process
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