ASB3 anticorps (AA 21-120) (Biotin)
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- Antigène Voir toutes ASB3 Anticorps
- ASB3 (Ankyrin Repeat and SOCS Box-Containing 3 (ASB3))
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Épitope
- AA 21-120
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ASB3 est conjugé à/à la Biotin
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Application
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Dog,Cow,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human ASB3
- Isotype
- IgG
- Top Product
- Discover our top product ASB3 Anticorps primaire
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- Indications d'application
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IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- ASB3 (Ankyrin Repeat and SOCS Box-Containing 3 (ASB3))
- Autre désignation
- ASB3 (ASB3 Produits)
- Synonymes
- anticorps ASB-3, anticorps 2400011J03Rik, anticorps Asb-3, anticorps fi36b12, anticorps zgc:56163, anticorps wu:fi36b12, anticorps ASB3, anticorps DKFZp459D0910, anticorps asb-3, anticorps asb3, anticorps ankyrin repeat and SOCS box containing 3, anticorps ankyrin repeat and SOCS box-containing 3, anticorps ankyrin repeat and SOCS box containing 3 S homeolog, anticorps ASB3, anticorps Asb3, anticorps asb3, anticorps asb3.S
- Sujet
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Synonyms: Ankyrin repeat and SOCS box containing 3, Ankyrin repeat and SOCS box containing protein 3, Ankyrin repeat and SOCS box protein 3, ASB-3, ASB3, ASB3_HUMAN, Weakly similar to ankyrin brain variant 2.
Background: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
- ID gène
- 51130
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