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NOD2 anticorps (AA 251-350) (Biotin)

NOD2 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN886421
  • Antigène Voir toutes NOD2 Anticorps
    NOD2 (Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))
    Épitope
    • 15
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 251-350
    Reactivité
    • 42
    • 6
    • 4
    Humain
    Hôte
    • 42
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 44
    • 2
    Polyclonal
    Conjugué
    • 20
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NOD2 est conjugé à/à la Biotin
    Application
    • 34
    • 16
    • 15
    • 7
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CARD15
    Isotype
    IgG
    Top Product
    Discover our top product NOD2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    NOD2 (Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))
    Autre désignation
    NOD2 (NOD2 Produits)
    Synonymes
    anticorps ACUG, anticorps BLAU, anticorps CARD15, anticorps CD, anticorps CLR16.3, anticorps IBD1, anticorps NLRC2, anticorps NOD2B, anticorps PSORAS1, anticorps Card15, anticorps F830032C23Rik, anticorps Nlrc2, anticorps caspase recruitment domain 15 protein, anticorps nucleotide binding oligomerization domain containing 2, anticorps nucleotide-binding oligomerization domain containing 2, anticorps TTHERM_01951320, anticorps NOD2, anticorps Nod2
    Sujet

    Synonyms: ACUG, Arthrocutaneouveal granulomatosis, BLAU, CARD15, Caspase recruitment domain protein 15, Caspase recruitment domain-containing protein 15, IBD1, Inflammatory bowel disease protein 1, LRR containing protein, LRR-containing protein, Nod2, NOD2 protein, NOD2_HUMAN, NOD2B, nucleotide binding oligomerization domain 2, nucleotide-binding oligomerization domain 2, Nucleotide-binding oligomerization domain-containing protein 2, PSORAS1.

    Background: Defects in NOD2 are the cause of sarcoidosis early-onset (EOS) . EOS is a form of sarcoidosis manifesting in children younger than 4 years of age. Sarcoidosis is an idiopathic, systemic, inflammatory disease characterized by the formation of immune granulomas in involved organs. Granulomas predominantly invade the lungs and the lymphatic system, but also skin, liver, spleen, eyes and other organs may be involved. Early-onset sarcoidosis is quite rare and has a distinct triad of skin, joint and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, early-onset sarcoidosis is progressive and in many cases causes severe complications, such as blindness, joint destruction and visceral involvement.

    ID gène
    64127
    UniProt
    Q9HC29
    Pathways
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome
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