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CCDC39 anticorps (Cy3)

CCDC39 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal Cy3
N° du produit ABIN887696
  • Antigène Voir toutes CCDC39 Anticorps
    CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))
    Reactivité
    • 31
    • 22
    • 13
    • 9
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 31
    Lapin
    Clonalité
    • 31
    Polyclonal
    Conjugué
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CCDC39 est conjugé à/à la Cy3
    Application
    • 30
    • 16
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Cow,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CCDC39
    Isotype
    IgG
    Top Product
    Discover our top product CCDC39 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))
    Autre désignation
    Ccdc39 (CCDC39 Produits)
    Synonymes
    anticorps 4921507O14Rik, anticorps AI447426, anticorps AI844750, anticorps D3Ertd789e, anticorps b2b1304Clo, anticorps b2b1735Clo, anticorps RGD1306277, anticorps CILD14, anticorps FAP59, anticorps coiled-coil domain containing 39, anticorps flagellar associated protein, anticorps Ccdc39, anticorps CCDC39, anticorps ccdc39, anticorps FAP59
    Sujet

    Synonyms: CCD39_HUMAN, Ccdc39, Coiled-coil domain-containing protein 39.

    Background: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly.Tissue specificity:Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis.Involvement in disease:Defects in CCDC39 are the cause of primary ciliary dyskinesia type 14 (CILD14) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia, reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.

    ID gène
    339829
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