Cyclic GMP anticorps (AbBy Fluor® 488)

N° du produit ABIN890284

Détail du produit anti-Cyclic GMP anticorps (AbBy Fluor® 488)

Antigène: Cyclic GMP (cGMP)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclic GMP est conjugé à/à la AbBy Fluor® 488

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Specificité: Due to the fact that BSA is used as the carrier, this antibody will cross-react with Albumin.

Réactivité croisée: Rat

Réactivité croisée (Details): cGMP

Purification: Purified by Protein A.

Immunogène: OVA conjugated cGMP

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Cyclic GMP

Antigène: Cyclic GMP (cGMP)

Autre désignation: Cgmp (cGMP Produits)

Classe de substances: Chemical

Sujet:

Synonyms: Cyclic GMP, Cyclic guanosine monophosphate, Guanosine 3 5 Cyclic Monophosphate.

Background: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).