CLASP2 anticorps (AA 1201-1294) (Biotin)

N° du produit ABIN891144

Détail du produit anti-CLASP2 anticorps (Biotin)

Antigène: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Épitope: AA 1201-1294

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLASP2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CLASP2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CLASP2

Antigène: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Autre désignation: CLASP2 (CLASP2 Produits)

Synonymes: anticorps zgc:77279, anticorps DKFZp459M112, anticorps 1500004F14Rik, anticorps 8030404L10Rik, anticorps C77448, anticorps CLASP2beta, anticorps mKIAA0627, anticorps cytoplasmic linker associated protein 2, anticorps CLIP associating protein 2, anticorps clasp2, anticorps CLASP2, anticorps Clasp2

Sujet:

Synonyms: CLASP 2, CLIP associating protein 2, Cytoplasmic linker associated protein 2, hOrbit2, KIAA0627, Multiple asters Mast like homolog 2, Protein Orbit homolog 2, CLAP2_HUMAN.

Background: CLASP2 is a microtubule plus end tracking protein that promotes the stabilization of dynamic microtubules and is required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. CLASP2 may act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3 kinase signaling. CLASP2 also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

ID gène: 23122

Pathways: Dynamique des Microtubules, Maintenance of Protein Location