CPEB1 anticorps (AA 451-550) (AbBy Fluor® 647)
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- Antigène Voir toutes CPEB1 Anticorps
- CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
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Épitope
- AA 451-550
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CPEB1 est conjugé à/à la AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human CPEB1
- Isotype
- IgG
- Top Product
- Discover our top product CPEB1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
- Autre désignation
- CPEB1 (CPEB1 Produits)
- Synonymes
- anticorps CEBP, anticorps CPE-BP1, anticorps CPEB, anticorps AU024112, anticorps Cpeb, anticorps mCPEB, anticorps CPEB1, anticorps cpeb1, anticorps ZOR-1, anticorps cepb1b, anticorps fd15c06, anticorps wu:fd15c06, anticorps zorba, anticorps cytoplasmic polyadenylation element binding protein 1, anticorps hypothetical protein, anticorps cytoplasmic polyadenylation element binding protein 1 L homeolog, anticorps cytoplasmic polyadenylation element binding protein 1b, anticorps cytoplasmic polyadenylation element binding protein 1 S homeolog, anticorps CPEB1, anticorps Cpeb1, anticorps cpeb1, anticorps LOAG_17395, anticorps cpeb1.L, anticorps cpeb1b, anticorps cpeb1.S
- Sujet
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Synonyms: CPE-binding protein 1, CPE-BP1, CPEB 1, CPEB, CPEB1, CPEB1 protein, CPEB1_HUMAN, Cytoplasmic polyadenylation binding protein 1, Cytoplasmic polyadenylation element binding protein, Cytoplasmic polyadenylation element binding protein 1, Cytoplasmic polyadenylation element-binding protein 1, h-CEBP, hCPEB-1
Background: Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA, a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites, those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.
- ID gène
- 64506
- Pathways
- Synaptic Membrane
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