Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Deltex Homolog 1 anticorps (AA 351-450) (AbBy Fluor® 488)

DTX1 Reactivité: Humain, Souris, Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 488
N° du produit ABIN893885
  • Antigène Voir toutes Deltex Homolog 1 (DTX1) Anticorps
    Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))
    Épitope
    • 15
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivité
    • 42
    • 24
    • 16
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 42
    • 1
    Lapin
    Clonalité
    • 43
    Polyclonal
    Conjugué
    • 15
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Deltex Homolog 1 est conjugé à/à la AbBy Fluor® 488
    Application
    • 31
    • 14
    • 13
    • 13
    • 9
    • 8
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Cow
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Deltex-1
    Isotype
    IgG
    Top Product
    Discover our top product DTX1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))
    Autre désignation
    Deltex 1 (DTX1 Produits)
    Synonymes
    anticorps hDx-1, anticorps Fxit1, anticorps mKIAA4160, anticorps deltex, anticorps dtx, anticorps xdtx1, anticorps deltex E3 ubiquitin ligase 1, anticorps deltex homolog 1 (Drosophila), anticorps deltex 1, E3 ubiquitin ligase, anticorps deltex 1 L homeolog, anticorps deltex 1 S homeolog, anticorps DTX1, anticorps dtx1, anticorps Dtx1, anticorps dtx1.L, anticorps dtx1.S
    Sujet

    Synonyms: hDx-1, E3 ubiquitin-protein ligase DTX1, Protein deltex-1, Deltex1, hDTX1, DTX1

    Background: Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.

    ID gène
    1840
    UniProt
    Q86Y01
    Pathways
    Signalisation Notch
Vous êtes ici:
Support technique