DOCK1 anticorps (AA 465-550) (Biotin)

N° du produit ABIN894254

Détail du produit anti-DOCK1 anticorps (Biotin)

Antigène: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Épitope: AA 465-550

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK1 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DOCK1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur DOCK1

Antigène: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Autre désignation: DOCK1 (DOCK1 Produits)

Synonymes: anticorps DOCK180, anticorps ced5, anticorps 9130006G06Rik, anticorps AI854900, anticorps D630004B07Rik, anticorps RGD1566072, anticorps dedicator of cytokinesis 1, anticorps dedicator of cytokinesis protein 1, anticorps dedicator of cyto-kinesis 1, anticorps DOCK1, anticorps Dock1, anticorps dock1, anticorps CpipJ_CPIJ002759

Sujet:

Synonyms: 180 kDa protein downstream of CRK, Ced5, Dedicator of Cytokinesis 1, Dedicator of cytokinesis protein 1, DOCK 1, DOCK-1, DOCK 180, DOCK1, DOCK1_HUMAN, DOCK180.

Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.

ID gène: 1793

Pathways: Signaling of Hepatocyte Growth Factor Receptor