FAM3C anticorps (AA 151-227) (Cy7)
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- Antigène Voir toutes FAM3C Anticorps
- FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))
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Épitope
- AA 151-227
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FAM3C est conjugé à/à la Cy7
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Rat
- Homologie
- Mouse,Dog,Cow,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human FAM3C
- Isotype
- IgG
- Top Product
- Discover our top product FAM3C Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))
- Autre désignation
- FAM3C (FAM3C Produits)
- Synonymes
- anticorps ILEI, anticorps D6Wsu176e, anticorps Ilei, anticorps wu:fb99h11, anticorps wu:fi35h03, anticorps zgc:55444, anticorps zgc:77090, anticorps family with sequence similarity 3 member C, anticorps family with sequence similarity 3, member C, anticorps family with sequence similarity 3 member C L homeolog, anticorps fam3c, anticorps FAM3C, anticorps Fam3c, anticorps fam3c.L
- Sujet
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Synonyms: Fam3c, FAM3C_HUMAN, family with sequence similarity 3, member C, GS3786,ILEI, Interleukin-like EMT inducer, Predicted osteoblast protein, Protein FAM3C.
Background: ILEI is a 227 amino acid, ubiquitously expressed protein containing an amino-terminal signal peptide. Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis. Also, overexpression of ILEI results in loss of ZO-1, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, which has been shown to influence loss of polarity and invasiveness. Due to this evidence, it is suspected that ILEI cooperates with oncogenic Ras to cause TGF-independent Emt and its overexpression is correlated with the invasion, metastasis and survival in a variety of cancers.
- ID gène
- 10447
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