Id2 anticorps (AA 31-134) (AbBy Fluor® 350)
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- Antigène Voir toutes Id2 Anticorps
- Id2 (Inhibitor of DNA Binding 2 (Id2))
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Épitope
- AA 31-134
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Id2 est conjugé à/à la AbBy Fluor® 350
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Specificité
- Due to the similarity of this protein with ID1, this antibody has a chance to have light cross-reactivity with ID1 due to a 77 % sequence similarity in the range of our immunogen.
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human GIG8/ID2
- Isotype
- IgG
- Top Product
- Discover our top product Id2 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Id2 (Inhibitor of DNA Binding 2 (Id2))
- Autre désignation
- ID2 (Id2 Produits)
- Synonymes
- anticorps AI255428, anticorps C78922, anticorps Idb2, anticorps bHLHb26, anticorps Ac2-300, anticorps GIG8, anticorps ID2A, anticorps ID2H, anticorps XId2, anticorps id2-A, anticorps inhibitor of DNA binding 2, anticorps inhibitor of DNA binding 2, HLH protein, anticorps inhibitor of DNA binding 2 L homeolog, anticorps Id2, anticorps ID2, anticorps id2.L
- Sujet
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Synonyms: GIG8, ID2A, ID2H, bHLHb26, DNA-binding protein inhibitor ID-2, Class B basic helix-loop-helix protein 26, Inhibitor of DNA binding 2, Inhibitor of differentiation 2, ID2
Background: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
- ID gène
- 3398
- UniProt
- Q02363
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