IER3 anticorps (AA 85-156) (AbBy Fluor® 488)

N° du produit ABIN901738

Détail du produit anti-IER3 anticorps (AbBy Fluor® 488)

Antigène: IER3 (Immediate Early Response 3 (IER3))

Épitope: AA 85-156

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IER3 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur IER3

Antigène: IER3 (Immediate Early Response 3 (IER3))

Autre désignation: IEX1 (IER3 Produits)

Synonymes: anticorps DIF-2, anticorps DIF2, anticorps GLY96, anticorps IEX-1, anticorps IEX-1L, anticorps IEX1, anticorps PRG1, anticorps AI663993, anticorps cI-3, anticorps gly96, anticorps IER3, anticorps Dif2, anticorps Iex1, anticorps Ler3, anticorps Prg1, anticorps immediate early response 3, anticorps IER3, anticorps Ier3

Sujet:

Synonyms: DIF2, IEX1, PRG1, DIF-2, GLY96, IEX-1, IEX-1L, Radiation-inducible immediate-early gene IEX-1, Differentiation-dependent gene 2 protein, Protein DIF-2, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, Protein PRG1, IER3

Background: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.

ID gène: 8870

UniProt: P46695

Pathways: Regulation of Carbohydrate Metabolic Process