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ILP-2 anticorps (AA 141-236) (AbBy Fluor® 647)

BIRC8 Reactivité: Rat IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 647
N° du produit ABIN902645
  • Antigène Voir toutes ILP-2 (BIRC8) Anticorps
    ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))
    Épitope
    • 14
    • 4
    • 4
    • 1
    AA 141-236
    Reactivité
    • 27
    • 18
    • 14
    Rat
    Hôte
    • 30
    • 2
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ILP-2 est conjugé à/à la AbBy Fluor® 647
    Application
    • 12
    • 12
    • 10
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ILP2
    Isotype
    IgG
    Top Product
    Discover our top product BIRC8 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))
    Autre désignation
    ILP2 (BIRC8 Produits)
    Synonymes
    anticorps ILP-2, anticorps ILP2, anticorps hILP2, anticorps baculoviral IAP repeat containing 8, anticorps BIRC8
    Sujet

    Synonyms: Baculoviral IAP repeat containing 8, Baculoviral IAP repeat containing protein 8, Baculoviral IAP repeat-containing protein 8, BIRC 8, BIRC8, BIRC8 protein, BIRC8_HUMAN, hILP 2, hILP2, IAP like protein 2, IAP-like protein 2, ILP 2, ILP-2, Inhibitor of apoptosis like protein 2, Inhibitor of apoptosis-like protein 2, Testis specic inhibitor of apoptosis, Testis-specic inhibitor of apoptosis.

    Background: Protects against apoptosis mediated by BAX.Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.

    ID gène
    112401
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