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KDM5B anticorps (AA 65-165) (AbBy Fluor® 488)

KDM5B Reactivité: Humain, Rat WB, FACS, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 488
N° du produit ABIN903568
  • Antigène Voir toutes KDM5B Anticorps
    KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
    Épitope
    • 15
    • 9
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-165
    Reactivité
    • 40
    • 26
    • 17
    • 1
    Humain, Rat
    Hôte
    • 45
    • 6
    Lapin
    Clonalité
    • 46
    • 5
    Polyclonal
    Conjugué
    • 22
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KDM5B est conjugé à/à la AbBy Fluor® 488
    Application
    • 40
    • 20
    • 15
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Rat
    Homologie
    Mouse,Dog,Cow,Pig,Horse,Chicken,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human KDM5B/Jarid1B
    Isotype
    IgG
    Top Product
    Discover our top product KDM5B Anticorps primaire
  • Indications d'application
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
    Autre désignation
    KDM5B (KDM5B Produits)
    Synonymes
    anticorps jarid1b, anticorps jarid1ba, anticorps id:ibd5050, anticorps wu:fd15c05, anticorps cb264, anticorps jarid1bb, anticorps plu1, anticorps wu:fc44h11, anticorps zgc:85741, anticorps JARID1B, anticorps CT31, anticorps PLU-1, anticorps PLU1, anticorps PUT1, anticorps RBBP2H1A, anticorps 2010009J12Rik, anticorps 2210016I17Rik, anticorps AW556288, anticorps D1Ertd202e, anticorps Jarid1b, anticorps Plu1, anticorps Rb-Bp2, anticorps mKIAA4034, anticorps RGD1565602, anticorps lysine (K)-specific demethylase 5Ba, anticorps lysine (K)-specific demethylase 5Bb, anticorps lysine demethylase 5B, anticorps lysine (K)-specific demethylase 5B, anticorps kdm5ba, anticorps kdm5bb, anticorps KDM5B, anticorps Kdm5b
    Sujet

    Synonyms: CT31, PLU1, PUT1, PLU-1, JARID1B, PPP1R98, RBBP2H1A, Lysine-specific demethylase 5B, Cancer/testis antigen 31, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, Retinoblastoma-binding protein 2 homolog 1, RBP2-H1, KDM5B, RBBP2H1

    Background: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).

    ID gène
    10765
    UniProt
    Q9UGL1
    Pathways
    L'effet Warburg
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