LAP3 anticorps (AA 131-230) (Biotin)

N° du produit ABIN904522

Détail du produit anti-LAP3 anticorps (Biotin)

Antigène: LAP3 (Cytosol Aminopeptidase (LAP3))

Épitope: AA 131-230

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LAP3 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LAP3

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur LAP3

Antigène: LAP3 (Cytosol Aminopeptidase (LAP3))

Autre désignation: LAP3 (LAP3 Produits)

Synonymes: anticorps LAP, anticorps LAPEP, anticorps PEPS, anticorps 2410015L10Rik, anticorps AA410100, anticorps LAP-3, anticorps Lap, anticorps Lapep, anticorps Pep-7, anticorps Pep-S, anticorps Pep7, anticorps Peps, anticorps cytosol aminopeptidase, anticorps leucine aminopeptidase 3, anticorps pepA, anticorps Plabr_1567, anticorps Dester_0800, anticorps Weevi_0186, anticorps Marky_0570, anticorps Halhy_2623, anticorps FsymDg_3217, anticorps Flexsi_2186, anticorps Runsl_3980, anticorps lap3, anticorps LAP3, anticorps Lap3

Sujet:

Synonyms: Cytosol aminopeptidase, LAP 3, LAP, LAPEP, Leucine aminopeptidase 3, Leucyl aminopeptidase, PEPS, Peptidase S, Proline aminopeptidase, Prolyl aminopeptidase, AMPL_HUMAN.

Background: LAP3 (leucine aminopeptidase 3), also known as LAPEP or PEPS, is a 519 amino acid protein that localizes to the cytoplasm and belongs to the peptidase M17 family. Existing as a homohexamer, LAP3 uses zinc as a cofactor to catalyze the release of an N-terminal proline from a target peptide and is, therefore, involved in the processing and turnover of intracellular proteins. Multiple isoforms of LAP3 exist due to alternative splicing events. The gene encoding LAP3 maps to human chromosome 4, which houses nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

ID gène: 51056