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MAP1LC3A/B anticorps (AA 21-121) (AbBy Fluor® 647)

Reactivité: Humain, Rat, Souris, Lapin WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 647
N° du produit ABIN904611
  • Antigène Tous les produits MAP1LC3A/B
    MAP1LC3A/B (MAP1LC3A,B)
    Épitope
    • 16
    • 14
    • 1
    • 1
    • 1
    AA 21-121
    Reactivité
    Humain, Rat, Souris, Lapin
    Hôte
    • 32
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp MAP1LC3A/B est conjugé à/à la AbBy Fluor® 647
    Application
    • 16
    • 14
    • 12
    • 12
    • 7
    • 6
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Lapin, Rat
    Homologie
    Dog,Cow,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human MAP1A/MAP1B LC3 B
    Isotype
    IgG
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    MAP1LC3A/B (MAP1LC3A,B)
    Autre désignation
    MAP1A/MAP1B LC3 A/B (MAP1LC3A/B Produits)
    Synonymes
    anticorps ATG8F, anticorps LC3B, anticorps MAP1A/1BLC3, anticorps MAP1LC3B-a, anticorps Map1lc3, anticorps Mpl3, anticorps zbs559, anticorps 1010001C15Rik, anticorps Atg8, anticorps LC3b, anticorps microtubule associated protein 1 light chain 3 beta, anticorps microtubule-associated protein 1 light chain 3 beta, anticorps MAP1LC3B, anticorps Map1lc3b
    Sujet

    Synonyms: MAP LC3 beta, LC3, Autophagy related protein LC3 A, Autophagy related protein LC3 B, Autophagy related ubiquitin like modier LC3 A, Autophagy related ubiquitin like modier LC3 B, MAP1 light chain 3 like protein 1, MAP1 light chain 3 like protein 2, MAP1A/1B light chain 3 A, MAP1A/1B light chain 3 B, MAP1A/1BLC3, MAP1A/MAP1B LC3 A, MAP1A/MAP1B LC3 B, MAP1ALC3, MAP1BLC3, MAP1LC3A, MAP1LC3B, Microtubule associated protein 1 light chain 3 alpha, Microtubule associated protein 1 light chain 3 beta, Microtubule associated proteins 1A/1B light chain 3, Microtubule associated proteins 1A/1B light chain 3A, Microtubule associated proteins 1A/1B light chain 3B.microtubule-associated proteins 1A/1B light chain 3 beta 2

    Background: A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, termed LC3-I and LC3-II, respectively. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy.

    ID gène
    81631, 84557
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