MASP1 anticorps (AA 20-120) (AbBy Fluor® 647)
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- Antigène Voir toutes MASP1 Anticorps
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
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Épitope
- AA 20-120
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MASP1 est conjugé à/à la AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Dog,Cow,Pig,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human MASP
- Isotype
- IgG
- Top Product
- Discover our top product MASP1 Anticorps primaire
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- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- Autre désignation
- Masp (MASP1 Produits)
- Synonymes
- anticorps AW048060, anticorps CCPII, anticorps Crarf, anticorps Masp1/3, anticorps 3MC1, anticorps CRARF, anticorps CRARF1, anticorps MAP1, anticorps MASP, anticorps MASP3, anticorps MAp44, anticorps PRSS5, anticorps RaRF, anticorps mannan-binding lectin serine peptidase 1, anticorps mannan binding lectin serine peptidase 1, anticorps Masp1, anticorps MASP1
- Sujet
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Synonyms: 3MC1, MAP1, MASP, RaRF, CRARF, MASP3, MAp44, PRSS5, CRARF1, Mannan-binding lectin serine protease 1, Complement factor MASP-3, Complement-activating component of Ra-reactive factor, Mannose-binding lectin-associated serine protease 1, MASP-1, Mannose-binding protein-associated serine protease, Ra-reactive factor serine protease p100, Serine protease 5, MASP1
Background: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
- ID gène
- 5648
- UniProt
- P48740
- Pathways
- Système du Complément
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