MBP anticorps (AA 69-85) (AbBy Fluor® 488)

N° du produit ABIN905814

Détail du produit anti-MBP anticorps (AbBy Fluor® 488)

Antigène: MBP

Épitope: AA 69-85

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBP est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Homologie: Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from Guinea Pig MBP

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MBP

Antigène: MBP

Abstract: MBP Produits

Synonymes: anticorps C76307, anticorps Hmbpr, anticorps R75289, anticorps golli-mbp, anticorps mld, anticorps shi, anticorps Mbps, anticorps cb274, anticorps fj33b11, anticorps mbp, anticorps wu:fj33b11, anticorps wu:fq15b02, anticorps zgc:136630, anticorps myelin basic protein, anticorps myelin basic protein a, anticorps MBP, anticorps Mbp, anticorps mbpa

Sujet:

Synonyms: MBP_CAVPO,Myelin Basic Protein, Myelin basic protien, GDB, Golli MBP, Hemopoietic MBP, HMBPR, HUGO, MBP, MGC99675, MLD, Myelin A1 Protein, Myelin Deficient, Myelin Membrane Encephalitogenic Protein, SHI, Shiverer, SP, MBP TAG, MBP-TAG

Background: Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.