Menin anticorps (AA 501-615) (AbBy Fluor® 555)
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- Antigène Voir toutes Menin (MEN1) Anticorps
- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
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Épitope
- AA 501-615
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Menin est conjugé à/à la AbBy Fluor® 555
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Dog,Cow,Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Menin
- Isotype
- IgG
- Top Product
- Discover our top product MEN1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
- Autre désignation
- Menin (MEN1 Produits)
- Synonymes
- anticorps MEAI, anticorps SCG2, anticorps menin, anticorps meai, anticorps scg2, anticorps AW045611, anticorps menin 1, anticorps menin 1 L homeolog, anticorps multiple endocrine neoplasia I, anticorps multiple endocrine neoplasia 1, anticorps MEN1, anticorps men1, anticorps men1.L, anticorps Men1
- Sujet
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Synonyms: MEAI, SCG2, Menin, MEN1
Background: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
- ID gène
- 4221
- UniProt
- O00255
- Pathways
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
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