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NCKAP1 anticorps (AA 1001-1132) (AbBy Fluor® 647)

NCKAP1 Reactivité: Souris WB Hôte: Lapin Polyclonal AbBy Fluor® 647
N° du produit ABIN907761
  • Antigène Voir toutes NCKAP1 Anticorps
    NCKAP1 (NCK Associated Protein 1 (NCKAP1))
    Épitope
    • 14
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1001-1132
    Reactivité
    • 33
    • 26
    • 11
    Souris
    Hôte
    • 46
    • 1
    Lapin
    Clonalité
    • 47
    Polyclonal
    Conjugué
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NCKAP1 est conjugé à/à la AbBy Fluor® 647
    Application
    • 36
    • 18
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Dog,Cow,Pig,Horse,Chicken,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human NCKAP1L
    Isotype
    IgG
    Top Product
    Discover our top product NCKAP1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    NCKAP1 (NCK Associated Protein 1 (NCKAP1))
    Autre désignation
    NCKAP1 (NCKAP1 Produits)
    Synonymes
    anticorps HEM2, anticorps NAP1, anticorps NAP125, anticorps p125Nap1, anticorps C79304, anticorps H19, anticorps Hem-2, anticorps Hem2, anticorps Nap1, anticorps mKIAA0587, anticorps mh19, anticorps NCK associated protein 1, anticorps NCK-associated protein 1, anticorps NCK-associated protein 1 L homeolog, anticorps NCKAP1, anticorps Nckap1, anticorps nckap1.L
    Sujet

    Synonyms: NCK associated protein 1, NCK associated protein 1, Membrane associated protein HEM2, Membrane-associated protein HEM-2, NAP 1, NAP1, NAP125, NCK associated protein, Nck-associated protein 1, Nckap1, NCKP1_HUMAN, p125Nap1.

    Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.

    ID gène
    10787
    UniProt
    P55160
    Pathways
    Signalisation RTK, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
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