NOC2L anticorps (AA 251-350) (AbBy Fluor® 488)
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- Antigène Voir toutes NOC2L Anticorps
- NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))
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Épitope
- AA 251-350
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NOC2L est conjugé à/à la AbBy Fluor® 488
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Cow,Sheep,Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human NOC2L
- Isotype
- IgG
- Top Product
- Discover our top product NOC2L Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))
- Autre désignation
- NOC2L (NOC2L Produits)
- Synonymes
- anticorps NET15, anticorps NET7, anticorps NIR, anticorps AA410003, anticorps AF155546, anticorps RGD1309387, anticorps NOC2 like nucleolar associated transcriptional repressor, anticorps NOC2-like nucleolar associated transcriptional repressor, anticorps NOC2L, anticorps Noc2l
- Sujet
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Synonyms: NIR, NOC2 like, Novel INHAT inhibitor of histone acetyltransferase repressor, Nucleolar complex associated 2 homolog S. cerevisiae, Protein NOC2 homolog, NOC2L_HUMAN.
Background: NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.
- ID gène
- 26155
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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