PCDHB13 anticorps (AA 151-250) (AbBy Fluor® 488)

N° du produit ABIN910252

Détail du produit anti-PCDHB13 anticorps (AbBy Fluor® 488)

Antigène: PCDHB13 (Protocadherin beta 13 (PCDHB13))

Épitope: AA 151-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHB13 est conjugé à/à la AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PCDHB13

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PCDHB13

Antigène: PCDHB13 (Protocadherin beta 13 (PCDHB13))

Autre désignation: PCDHB13 (PCDHB13 Produits)

Synonymes: anticorps PCDH-BETA13, anticorps Pcdh3, anticorps Pcdbh6, anticorps PcdhbM, anticorps PCDHB13, anticorps protocadherin beta 13, anticorps protocadherin beta 12, anticorps protocadherin beta-8, anticorps PCDHB13, anticorps Pcdhb12, anticorps Pcdhb13, anticorps LOC518612

Sujet:

Synonyms: Protocadherin beta 13, PCDH BETA13, PCDHB13, PCDBD_HUMAN

Background: Cadherins are calcium-dependent cell-cell adhesion molecules, and protocadherins constitute a subfamily of nonclassic cadherins. Protocadherin beta 13 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

ID gène: 56123