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PLCz1 anticorps (AA 351-450) (AbBy Fluor® 350)

PLCz1 Reactivité: Rat IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 350
N° du produit ABIN911373
  • Antigène Voir toutes PLCz1 Anticorps
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    Épitope
    • 14
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivité
    • 20
    • 14
    • 4
    Rat
    Hôte
    • 33
    • 2
    Lapin
    Clonalité
    • 33
    • 2
    Polyclonal
    Conjugué
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PLCz1 est conjugé à/à la AbBy Fluor® 350
    Application
    • 12
    • 12
    • 12
    • 10
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PLCZ1
    Isotype
    IgG
    Top Product
    Discover our top product PLCz1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    Autre désignation
    PLCZ1 (PLCz1 Produits)
    Synonymes
    anticorps PLC-zeta-1, anticorps PLCZ1, anticorps 1700041H07Rik, anticorps PLCzeta, anticorps NYD-SP27, anticorps PLCZ, anticorps phospholipase C zeta 1, anticorps phospholipase C, zeta 1, anticorps PLCZ1, anticorps Plcz1
    Sujet

    Synonyms: PLCzeta, NYD-SP27, PLC-zeta-1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, Phosphoinositide phospholipase C-zeta-1, Phospholipase C-zeta-1, Testis-development protein NYD-SP27, PLCZ1, PLCZ1_HUMAN

    Background: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.

    ID gène
    89869
    UniProt
    Q86YW0
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