Seladin 1 anticorps (AbBy Fluor® 488)
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- Antigène Voir toutes Seladin 1 (DHCR24) Anticorps
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Seladin 1 est conjugé à/à la AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Souris, Porc, Rat
- Homologie
- Human,Dog,Cow,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Seladin 1
- Isotype
- IgG
- Top Product
- Discover our top product DHCR24 Anticorps primaire
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- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
- Autre désignation
- Seladin 1 (DHCR24 Produits)
- Synonymes
- anticorps MGC82737, anticorps zgc:101638, anticorps DCE, anticorps Nbla03646, anticorps SELADIN1, anticorps seladin-1, anticorps 2310076D10Rik, anticorps 5830417J06Rik, anticorps mKIAA0018, anticorps 24-dehydrocholesterol reductase, anticorps 24-dehydrocholesterol reductase S homeolog, anticorps delta(24)-sterol reductase, anticorps DHCR24, anticorps dhcr24.S, anticorps dhcr24, anticorps LOC5575872, anticorps CpipJ_CPIJ000670, anticorps Dhcr24
- Sujet
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Synonyms: Seladin1, Seladin-1, DHCR24, 24 dehydrocholesterol reductase, 3-beta-hydroxysterol delta-24-reductase, DCE, Desmosterol to cholesterol enzyme, Diminuto dwarf1 homolog, SELADIN1, Selective AD indicator 1, Selective Alzheimer's Disease Indicator 1.
Background: Seladin 1 is highly expressed in brain, adrenal tissues and adrenal tumours, where this enzyme catalyzes the reduction of the delta-24 double bond of sterol intermediates such as desmosterol, during cholesterol biosynthesis. In addition, Seladin 1 has an anti-apoptotic function by reducing caspase 3 activity during oxidative stress-induced apoptosis and protecting cells against amyloid-beta peptide-induced apoptosis. Several studies have identified a reduction in expression levels of this enzyme in brain regions affected by Alzheimer's disease (hippocampus and the subventricular zone).
- ID gène
- 1718
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