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Sphingomyelin Synthase 1 anticorps (AA 331-413) (AbBy Fluor® 647)

SGMS1 Reactivité: Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 647
N° du produit ABIN916243
  • Antigène Voir toutes Sphingomyelin Synthase 1 (SGMS1) Anticorps
    Sphingomyelin Synthase 1 (SGMS1)
    Épitope
    • 14
    • 8
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 331-413
    Reactivité
    • 28
    • 20
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Souris
    Hôte
    • 42
    Lapin
    Clonalité
    • 42
    Polyclonal
    Conjugué
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Sphingomyelin Synthase 1 est conjugé à/à la AbBy Fluor® 647
    Application
    • 38
    • 20
    • 15
    • 12
    • 12
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Dog,Cow,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Sphingomyelin Synthase 1
    Isotype
    IgG
    Top Product
    Discover our top product SGMS1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Sphingomyelin Synthase 1 (SGMS1)
    Autre désignation
    Sphingomyelin Synthase 1 (SGMS1 Produits)
    Synonymes
    anticorps MGC81436, anticorps TMEM23, anticorps MOB, anticorps MOB1, anticorps SMS1, anticorps hmob33, anticorps 9530058O11Rik, anticorps AI841905, anticorps C80702, anticorps Mob, anticorps Sms1, anticorps Sor1, anticorps Tmem23, anticorps sphingomyelin synthase 1, anticorps sphingomyelin synthase 1 S homeolog, anticorps phosphatidylcholine:ceramide cholinephosphotransferase 1, anticorps SGMS1, anticorps sgms1.S, anticorps LOC100013212, anticorps Sgms1
    Sujet

    Synonyms: MOB, MOB1, SMS1, TMEM23, hmob33, Phosphatidylcholine:ceramide cholinephosphotransferase 1, Medulla oblongata-derived protein, Protein Mob, Sphingomyelin synthase 1, Transmembrane protein 23, SGMS1

    Background: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

    ID gène
    259230
    UniProt
    Q86VZ5
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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