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Syncytin A (SYNA) anticorps (AbBy Fluor® 647)

SYNA Reactivité: Humain WB Hôte: Lapin Polyclonal AbBy Fluor® 647
N° du produit ABIN916976
  • Antigène Voir toutes Syncytin A (SYNA) Anticorps
    Syncytin A (SYNA)
    Reactivité
    • 15
    • 6
    • 3
    Humain
    Hôte
    • 18
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AbBy Fluor® 647
    Application
    • 18
    • 9
    • 6
    • 3
    Western Blotting (WB)
     Réactivité croisée
    Humain, Souris
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Syncytin 1
    Isotype
    IgG
    Top Product
    Discover our top product SYNA Anticorps primaire
  • Indications d'application
    IF(IHC-P): 1:50-200
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Syncytin A (SYNA)
    Autre désignation
    Syncytin 1 (SYNA Produits)
    Synonymes
    anticorps Gm453, anticorps Gm52, anticorps syncytin-A, anticorps syncytin a, anticorps Syna
    Sujet

    Synonyms: ENV, ENVW, HERVW, ERVWE1, HERV7Q, HERV-7q, HERVWENV, HERV-W-ENV, Syncytin-1, Endogenous retrovirus group W member 1, Env-W, Envelope polyprotein gPr73, Enverin, HERV-7q Envelope protein, HERV-W envelope protein, HERV-W_7q21.2 provirus ancestral Env polyprotein, Syncytin, ERVW-1

    Background: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5 (PubMed:10708449, PubMed:12050356, PubMed:23492904). Endogenous envelope proteins may have kept, lost or modified their original function during evolution. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein (SU) mediates receptor recognition, while the transmembrane protein (TM) acts as a class I viral fusion protein. The protein may have at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of membranes.

    ID gène
    30816
    UniProt
    Q9UQF0
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