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TXN2 anticorps (AA 101-166) (AbBy Fluor® 555)

TXN2 Reactivité: Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 555
N° du produit ABIN917568
  • Antigène Voir toutes TXN2 Anticorps
    TXN2 (Thioredoxin 2 (TXN2))
    Épitope
    • 14
    • 9
    • 8
    • 6
    • 3
    • 1
    AA 101-166
    Reactivité
    • 37
    • 28
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Rat
    Hôte
    • 51
    • 1
    Lapin
    Clonalité
    • 50
    • 2
    Polyclonal
    Conjugué
    • 19
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TXN2 est conjugé à/à la AbBy Fluor® 555
    Application
    • 38
    • 15
    • 12
    • 12
    • 12
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Thioredoxin 2
    Isotype
    IgG
    Top Product
    Discover our top product TXN2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    TXN2 (Thioredoxin 2 (TXN2))
    Autre désignation
    Thioredoxin 2 (TXN2 Produits)
    Synonymes
    anticorps MT-TRX, anticorps MTRX, anticorps TRX2, anticorps 31884, anticorps CG31884, anticorps CG3864, anticorps DTrx-2, anticorps DmTrx-2, anticorps DmelTrx-2, anticorps Dmel\\CG31884, anticorps Trx, anticorps anon-WO0118547.188, anticorps dmtrx-2, anticorps 2510006J11Rik, anticorps AI788873, anticorps Trx2, anticorps zgc:77127, anticorps thioredoxin 2, anticorps thioredoxin-2, anticorps thiol reductase thioredoxin, anticorps thioredoxin 2 L homeolog, anticorps TXN2, anticorps Trx-2, anticorps LOC409451, anticorps VPA0972, anticorps VS_RS18125, anticorps VCD_000568, anticorps VEA_000083, anticorps trx2, anticorps Txn2, anticorps txn2, anticorps txn2.L
    Sujet

    Synonyms: mitochondrial thioredoxin, MT-TRX, MTRX, thioredoxin 2 precursor, Thioredoxin mitochondrial, Thioredoxin2, TRX 2, TRX2, TXN 2, TXN2.

    Background: Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1. Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

    ID gène
    25828
    Pathways
    Cell RedoxHomeostasis
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