TUSC2 anticorps (AA 31-100) (AbBy Fluor® 555)
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- Antigène Voir toutes TUSC2 Anticorps
- TUSC2 (Tumor Suppressor Candidate 2 (TUSC2))
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Épitope
- AA 31-100
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TUSC2 est conjugé à/à la AbBy Fluor® 555
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human TUSC2
- Isotype
- IgG
- Top Product
- Discover our top product TUSC2 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- TUSC2 (Tumor Suppressor Candidate 2 (TUSC2))
- Autre désignation
- TUSC2 (TUSC2 Produits)
- Synonymes
- anticorps C3orf11, anticorps FUS1, anticorps PAP, anticorps PDAP2, anticorps TUSC2, anticorps 1190001E22Rik, anticorps AA407686, anticorps Fus1, anticorps Lgcc, anticorps Pdap2, anticorps zgc:92701, anticorps zgc:153746, anticorps tumor suppressor candidate 2, anticorps tumor suppressor candidate 2 L homeolog, anticorps tumor suppressor candidate 2b, anticorps tumor suppressor candidate 2a, anticorps TUSC2, anticorps tusc2.L, anticorps Tusc2, anticorps tusc2b, anticorps tusc2a
- Sujet
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Synonyms: C3orf11, FUS1, Fusion 1 protein, PAP, PDAP2, PDGFA associated protein 2, Tumor suppressor candidate 2, TUSC 2, TUSC2_HUMAN.
Background: TUSC2/FUS1 is a novel tumor suppressor gene identified in the human chromosome 3p21.3 region where allele losses and genetic alterations occur early and frequently for many human cancers. Expression of TUSC2 protein is absent or reduced in the majority of lung cancers and premalignant lung lesions. Restoration of TUSC2 function in 3p21.3-deficient non-small cell lung carcinoma cells significantly inhibits tumor cell growth by induction of apoptosis and alteration of cell cycle kinetics. TUSC2 may induce apoptosis through the activation of the intrinsic mitochondrial-dependent and Apaf-1-associated pathways and inhibit the function of protein tyrosine kinases including EGFR, PDGFR, AKT, c-Abl, and c-Kit.
- ID gène
- 11334
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