UBE2V1 anticorps (AA 51-147) (AbBy Fluor® 555)
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- Antigène Voir toutes UBE2V1 Anticorps
- UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
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Épitope
- AA 51-147
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp UBE2V1 est conjugé à/à la AbBy Fluor® 555
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Rat
- Homologie
- Mouse,Sheep,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human UBE2V1
- Isotype
- IgG
- Top Product
- Discover our top product UBE2V1 Anticorps primaire
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- Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
- Autre désignation
- UBE2V1 (UBE2V1 Produits)
- Synonymes
- anticorps CIR1, anticorps CROC-1, anticorps CROC1, anticorps UBE2V, anticorps UEV-1, anticorps UEV1, anticorps UEV1A, anticorps 0610011J09Rik, anticorps AI256840, anticorps D7Bwg1382e, anticorps CROC-1B, anticorps ubiquitin conjugating enzyme E2 V1, anticorps ubiquitin-conjugating enzyme E2 variant 1, anticorps UBE2V1, anticorps ube2v1, anticorps Ube2v1
- Sujet
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Synonyms: CIR1, CROC-1, CROC1, CROC1A, TRAF6-regulated IKK activator 1 beta Uev1A, UB2V1_HUMAN, UBE2V 1, UBE2V, UBE2V1, Ubiquitin conjugating enzyme E2 variant 1, Ubiquitin-conjugating enzyme E2 variant 1, UEV-1, UEV1.
Background: Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
- ID gène
- 7335
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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