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HBxAg anticorps (AbBy Fluor® 488)

HBxAg Reactivité: Hepatitis B Virus (HBV) WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 488
N° du produit ABIN920133
  • Antigène Tous les produits HBxAg
    HBxAg (Hepatitis B Virus X Antigen (HBxAg))
    Reactivité
    • 21
    • 7
    • 7
    • 7
    • 4
    Hepatitis B Virus (HBV)
    Hôte
    • 16
    • 16
    Lapin
    Clonalité
    • 16
    • 16
    Polyclonal
    Conjugué
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HBxAg est conjugé à/à la AbBy Fluor® 488
    Application
    • 23
    • 12
    • 12
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Virus
    Réactivité croisée (Details)
    Hepatitis B virus
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from Hepatitis B virus X protein
    Isotype
    IgG
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    HBxAg (Hepatitis B Virus X Antigen (HBxAg))
    Autre désignation
    Hepatitis B Virus X Protein (HBxAg Produits)
    Classe de substances
    Viral Protein
    Sujet

    Synonyms: HBX, pre-X protein, HB-X, X protein, HBV X protein, X protein [Hepatitis B virus].

    Background: Multifunctional protein that may modulate protein degradation pathways, apoptosis, transcription, signal transduction, cell cycle progress, and genetic stability by directly or indirectly interacting with hosts factors. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. By binding to human DDB1, may affect cell viability and stimulate genome replication. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modulate apoptosis by binding human CFLAR, a key regulator of the death-inducing signaling complex (DISC). Moderately stimulates transcription of many different viral and cellular transcription elements. Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT. May bind bZIP transcription factors like CREB1 (By similarity).

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