ZWINT anticorps (AA 85-170) (Biotin)

N° du produit ABIN920497

Détail du produit anti-ZWINT anticorps (Biotin)

Antigène: ZWINT (ZW10 Interactor (ZWINT))

Épitope: AA 85-170

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZWINT est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ZWINT

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ZWINT

Antigène: ZWINT (ZW10 Interactor (ZWINT))

Autre désignation: ZWINT (ZWINT Produits)

Synonymes: anticorps ZWINT, anticorps HZwint-1, anticorps KNTC2AP, anticorps ZWINT1, anticorps 2010007E07Rik, anticorps 2600001N01Rik, anticorps D10Ertd749e, anticorps Zwint-1, anticorps Sip30, anticorps ZW10 interacting kinetochore protein, anticorps ZW10 interactor, anticorps ZWINT, anticorps Zwint

Sujet:

Synonyms: HZwint1, KNTC 2 AP, KNTC2AP, MGC 117174, MGC117174, ZW10 interacting protein 1, ZW10 interactor, ZWINT 1, ZWINT1, ZWINT-1, ZWINT_HUMAN.

Background: ZWINT is a component of the MIS12 complex, which is required for kinetochore function and spindle checkpoint activity. ZWINT interacts with ZW10 and targets it to the kinetochore at prometaphase. ZWINT is detectable on the kinetochore till late anaphase. Inhibition of ZWINT expression results in chromosome missegregation, spindle checkpoint failure and, ultimately, cell death upon cytokinesis.

ID gène: 11130