TIMELESS anticorps (C-Term)

N° du produit ABIN925900

Détail du produit anti-TIMELESS anticorps

Antigène: TIMELESS (Timeless Homolog (TIMELESS))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Drosophila melanogaster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMELESS est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Rat (Rattus), Souris, Mouche des fruits (Drosophila melanogaster), Chien

Immunogène: TIMELESS antibody was raised in rabbit using the C terminal of TIMELESS as the immunogen

Information d'application

Indications d'application: WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

TIMELESS Blocking Peptide, catalog no. 33R-2343, is also available for use as a blocking control in assays to test for specificity of this TIMELESS antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur TIMELESS

Antigène: TIMELESS (Timeless Homolog (TIMELESS))

Autre désignation: TIMELESS (TIMELESS Produits)

Sujet: The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein. Synonyms: Polyclonal TIMELESS antibody, Anti-TIMELESS antibody, timeless homolog, Drosophila antibody.

Pathways: Protein targeting to Nucleus, Photoperiodism