MAFK anticorps (N-Term)

N° du produit ABIN925961

Détail du produit anti-MAFK anticorps

Antigène: MAFK (Transcription Factor MafK (MAFK))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAFK est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Rat (Rattus), Chien, Poulet, Grenouille, Poisson zebré (Brachydanio rerio), Boeuf (Vache)

Immunogène: MAFK antibody was raised in rabbit using the N terminal of MAFK as the immunogen

Information d'application

Indications d'application: WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

MAFK Blocking Peptide, catalog no. 33R-4314, is also available for use as a blocking control in assays to test for specificity of this MAFK antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur MAFK

Antigène: MAFK (Transcription Factor MafK (MAFK))

Autre désignation: MAFK (MAFK Produits)

Synonymes: anticorps NFE2U, anticorps P18, anticorps AW061068, anticorps NF-E2, anticorps Nfe2u, anticorps MAF bZIP transcription factor K, anticorps v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian), anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K, anticorps Mafk, anticorps MAFK, anticorps mafk

Sujet: The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2. NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, PBGD and FECH. NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG, or MafK) and p45. Both subunits are members of the activator protein-1 superfamily of bZIP proteins. Maf homodimers suppress transcription at NFE2 sites. Synonyms: Polyclonal MAFK antibody, Anti-MAFK antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog K, avian antibody, FLJ32205 antibody, MGC71717 antibody, NFE2U antibody, P18 antibody.