WWOX anticorps (C-Term)

N° du produit ABIN926732

Détail du produit anti-WWOX anticorps

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWOX est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: WWOX antibody was raised in rabbit using the C terminal of WWOX as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

WWOX Blocking Peptide, catalog no. 33R-10313, is also available for use as a blocking control in assays to test for specificity of this WWOX antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur WWOX

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Autre désignation: WWOX (WWOX Produits)

Synonymes: anticorps CG7221, anticorps DmWWOX, anticorps Dmel\\CG7221, anticorps anon-EST:Posey177, anticorps GB11795, anticorps WWOX, anticorps D16S432E, anticorps FOR, anticorps FRA16D, anticorps HHCMA56, anticorps PRO0128, anticorps SDR41C1, anticorps WOX1, anticorps zgc:55975, anticorps 5330426P09Rik, anticorps 9030416C10Rik, anticorps WW domain containing oxidoreductase, anticorps WW domain-containing oxidoreductase, anticorps Wwox, anticorps LOC411815, anticorps WWOX, anticorps CpipJ_CPIJ004939, anticorps MCYG_01584, anticorps VDBG_05631, anticorps VDBG_01326, anticorps VDBG_06753, anticorps Tsp_03967, anticorps LOC100284583, anticorps wwox

Sujet: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms. Synonyms: Polyclonal WWOX antibody, Anti-WWOX antibody, WW domain containing oxidoreductase antibody, D16S432E antibody, FOR antibody, FRA16D antibody, HHCMA56 antibody, PRO0128 antibody, SDR41C1 antibody, WOX1 antibody.