FGD1 anticorps (C-Term)

N° du produit ABIN927334

Détail du produit anti-FGD1 anticorps

Antigène: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Épitope: C-Term

Reactivité: Humain, Boeuf (Vache), Chien, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGD1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Rat (Rattus), Boeuf (Vache), Chien

Purification: Purified

Immunogène: FGD1 antibody was raised in rabbit using the C terminal of FGD1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

FGD1 Blocking Peptide, catalog no. 33R-9977, is also available for use as a blocking control in assays to test for specificity of this FGD1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur FGD1

Antigène: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Autre désignation: FGD1 (FGD1 Produits)

Synonymes: anticorps AAS, anticorps FGDY, anticorps MRXS16, anticorps ZFYVE3, anticorps FYVE, RhoGEF and PH domain containing 1, anticorps FGD1, anticorps Fgd1, anticorps fgd1

Sujet: FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. Synonyms: Polyclonal FGD1 antibody, Anti-FGD1 antibody, FYVE, RhoGEF and PH domain containing 1, faciogenital dysplasia antibody.

Pathways: Neurotrophin Signaling Pathway