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ACD anticorps (C-Term)

ACD Reactivité: Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN927647
  • Antigène Voir toutes ACD Anticorps
    ACD (Adrenocortical Dysplasia Homolog (ACD))
    Épitope
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 32
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 1
    Souris
    Hôte
    • 26
    • 7
    • 1
    Lapin
    Clonalité
    • 29
    • 5
    Polyclonal
    Conjugué
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ACD est non-conjugé
    Application
    • 23
    • 10
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Purified
    Immunogène
    Acd antibody was raised in rabbit using the c terminal of Acd as the immunogen
    Top Product
    Discover our top product ACD Anticorps primaire
  • Indications d'application
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Commentaires

    Acd Blocking Peptide, catalog no. 33R-7345, is also available for use as a blocking control in assays to test for specificity of this Acd antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Antigène
    ACD (Adrenocortical Dysplasia Homolog (ACD))
    Autre désignation
    Acd (ACD Produits)
    Synonymes
    anticorps PIP1, anticorps PTOP, anticorps TINT1, anticorps TPP1, anticorps ACD, anticorps ACD, shelterin complex subunit and telomerase recruitment factor, anticorps adrenocortical dysplasia, anticorps ACD, anticorps Acd
    Sujet
    Acd is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.Acd promotes binding of POT1 to single-stranded telomeric DNA.Acd modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomer elongation by increasing telomerase processivity.Acd plays a role in shelterin complex assembly. Acd may play an essential role in organogenesis of the developing embryo. Synonyms: Polyclonal Acd antibody, Anti-Acd antibody, adrenocortical dysplasia antibody.
    Pathways
    Telomere Maintenance
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