RENT2/UPF2 anticorps (N-Term)

N° du produit ABIN927943

Détail du produit anti-RENT2/UPF2 anticorps

Antigène: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RENT2/UPF2 est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: UPF2 antibody was raised in rabbit using the N terminal of UPF2 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur RENT2/UPF2

Antigène: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Autre désignation: UPF2 (UPF2 Produits)

Synonymes: anticorps HUPF2, anticorps RENT2, anticorps smg-3, anticorps UPF2, regulator of nonsense mediated mRNA decay, anticorps UPF2 regulator of nonsense transcripts homolog (yeast), anticorps UPF2, anticorps Upf2, anticorps upf2

Sujet: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein. Synonyms: Polyclonal UPF2 antibody, Anti-UPF2 antibody, UPF2 regulator of nonsense transcripts homolog, yeast antibody, DKFZp434D222 antibody, HUPF2 antibody, KIAA1408 antibody, MGC138834 antibody, MGC138835 antibody, RENT2 antibody, smg-3 antibody.