PSMC3IP anticorps (C-Term)

N° du produit ABIN928182

Détail du produit anti-PSMC3IP anticorps

Antigène: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Épitope: C-Term

Reactivité: Souris, Humain, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMC3IP est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Rat (Rattus), Grenouille, Chien, Poulet, Boeuf (Vache), Poisson zebré (Brachydanio rerio)

Purification: Purified

Immunogène: PSMC3 IP antibody was raised in rabbit using the C terminal of PSMC3 P as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

PSMC3IP Blocking Peptide, catalog no. 33R-7037, is also available for use as a blocking control in assays to test for specificity of this PSMC3IP antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur PSMC3IP

Antigène: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Autre désignation: PSMC3IP (PSMC3IP Produits)

Sujet: PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3. Synonyms: Polyclonal PSMC3IP antibody, Anti-PSMC3IP antibody, PSMC3 interacting protein antibody, GT198 antibody, HOP2 antibody, TBPIP antibody.